(Wow, it's actually been over three years since the last post on this WWYD board.
You used to add a survey with the tile icons as options. There's hardly enough active posters to make that worthwhile now - although perhaps some people who don't want to make a post would at least be happy to give a survey response?
I generally didn't participate in these threads either but I feel that I should probably step up now!)
I'd discard the 1 and 2, maybe the 2 first as that's slightly more useful to other players.
You keep two complete sets and a pair, leaving you with a couple of two-sided shapes.
Several of the tiles they need are gone, but if you were playing with red fives you might get one for the Dots.
It's probably not worth declaring Riichi but at least if you make Tenpai you have a chance for a Pinfu win or points in a draw.
You wouldn't have many chances to make the 123 Iipeikou and if you completed another set first you'd lose the Pinfu potential.
I'm wary that the player to the right could be hoarding Craks, although probably not with a half-flush / flush as they discarded honours first.
With all your ones and nines it's too late to drop all the terminals and rebuild for Tanyao. Maybe if you had more turns, several Dora and no other Yaku.
It'd be nice to work the Dots into a three-sided wait or Itsu but again it's getting late and three of the 2 are out already.